In Layup's "Mona Lisa," the artist reflects on the aftermath of a breakup, inspired by the end of a high school sweetheart relationship. The song portrays the artist's acknowledgment of the emotional pain, while also recognizing and admiring the strength of the former partner. There's a wistful desire to still be with her, and the lyrics convey a sense of longing intertwined with an appreciation for the resilience displayed during the separation. The song serves as a poignant narrative of heartbreak, reminiscing about a past love with a mix of regret and admiration.